At the 2014 American Academy of Anti-Aging, we were lucky to interview Dr. Sandy Chang, MD, PhD, who is a leading researcher in the field of telomere biology.
In this first segment, Dr. Chang explains that we really don’t know what the normal human birth endowment of telomere length is and we then discuss why lab mice have abnormally long telomeres and are therefore not a good model to study our aging.
Finally, he touches upon this paper by his mentor, Dr. Ronald DePinho, in which the latter engineered mice to age with telomere attrition (like humans), and then by turning on telomerase, reversed those signs of aging.
Here is a video in which the now president of the MD Anderson Cancer Center explains telomeres to a complete idiot (whom I will miss so very much)
http://thecolbertreport.cc.com/videos/i48v1q/ronald-depinho
CAN YOU HELP ME SPREAD THE WORD?
As an aside, if you are one of the thousands of people that are reached by my blog and you know some very influential or famous people who have seen my videos or read my book, please ask then to pen a private, for the publisher’s eyes only, endorsement letter of what I do.
That’s because I am planning a second, “breakout” book and in order to get a book deal, I need to drop some names and sadly, despite the many über-famous people who have directly or indirectly benefited from my videos and from taking TA-65 in particular, they remain in the shadows (even as their wrinkles cast fewer of them.)
When I see the excitement over the next new thing (like David Sinclair), I realize that TA-65 has been out for seven years and it has yet to become widely accepted despite my best efforts in social media, video production, blogging, speaking, and self-publishing. Sadly, I realize that without publishing a commercially-successful title, the idea of telomerase activation could become another “also ran” like the now passé French Paradox and the red herring of red wine and resveratrol.
I had an anti-aging MD tell me only week that Telomeres were “so 5 years ago!” and given the 2009 Nobel Prize and this Harvard Mice study being 5-6 years ago, she may have been right.
If you think telomeres and telomerase shouldn’t be cast upon the dustbin of science like pet rocks or mood rings, then tell someone at TED or TEDMED to book me and ask that really famous person you know if they will write a private letter of endorsement for what I’m doing so that I can get obtain a book contract.
Thank you for your help in this matter, which is very time sensitive.